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pentobarbital will minimize the extent or influence of glecaprevir/pibrentasvir by influencing hepatic/intestinal enzyme CYP3A4 metabolism.pentobarbital will lower the level or result of ketoconazole by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Significance Mysterious.pentobarbital will reduce the level or effect of ixabepilon